Nicotine Effects in Adolescence and Adulthood on Cognition and α4β2-Nicotinic Receptors in the Neonatal Ventral Hippocampal Lesion Rat Model of Schizophrenia

RATIONAL: Nicotine use in schizophrenia has traditionally been explained as ‘self-medication’ of cognitive and/or nicotinic acetylcholinergic receptor (nAChR) abnormalities. OBJECTIVES: We test this hypothesis in a neurodevelopmental rat model of schizophrenia that shows increased addiction behavior...

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Bibliographic Details
Published in:Psychopharmacology (Berl)
Main Authors: Berg, Sarah A., Sentir, Alena M., Bell, Richard L., Engleman, Eric A., Chambers, R. Andrew
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412763/
https://ncbi.nlm.nih.gov/pubmed/25388292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3800-2
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