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Human Adipose-Tissue Derived Stromal Cells in Combination with Hypoxia Effectively Support Ex Vivo Expansion of Cord Blood Haematopoietic Progenitors

The optimisation of haematopoietic stem and progenitor cell expansion is on demand in modern cell therapy. In this work, haematopoietic stem/progenitor cells (HSPCs) have been selected from unmanipulated cord blood mononuclear cells (cbMNCs) due to adhesion to human adipose-tissue derived stromal ce...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Andreeva, Elena R., Andrianova, Irina V., Sotnezova, Elena V., Buravkov, Sergey V., Bobyleva, Polina I., Romanov, Yury A., Buravkova, Ludmila B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412539/
https://ncbi.nlm.nih.gov/pubmed/25919031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124939
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