Reversal of multidrug resistance in MCF-7/Adr cells by codelivery of doxorubicin and BCL2 siRNA using a folic acid-conjugated polyethylenimine hydroxypropyl-β-cyclodextrin nanocarrier

Systemic administration of chemotherapy for cancer often faces drug resistance, limiting its applications in cancer therapy. In this study, we developed a simple multifunctional nanocarrier based on polyethylenimine (PEI) to codeliver doxorubicin (DOX) and BCL2 small interfering RNA (siRNA) for over...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Li, Jin-Ming, Zhang, Wei, Su, Hua, Wang, Yuan-Yuan, Tan, Cai-Ping, Ji, Liang-Nian, Mao, Zong-Wan
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412489/
https://ncbi.nlm.nih.gov/pubmed/25960653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S67146
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