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Synthesis of a Disulfonated Derivative of Cucurbit[7]uril and Investigations of its Ability to Solubilize Insoluble Drugs

Cucurbit[7]uril (CB[7]) is currently being investigated as a solubilizing agent for insoluble drugs. We recently found that acyclic CB[n]-type receptors that bear sulfonate solubilizing groups are well suited for this application. Herein, we report cucurbit[7]uril derivative (1) that bears two sulfo...

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Detalhes bibliográficos
Publicado no:Supramol Chem
Main Authors: Robinson, Elizabeth L., Zavalij, Peter Y., Isaacs, Lyle
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412466/
https://ncbi.nlm.nih.gov/pubmed/25937787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10610278.2014.940952
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