NLRP12 negatively regulates autoinflammatory disease by modulating interleukin-4 production in T cells

Missense mutations in the nucleotide-binding oligomerization domain (NOD)-like receptor pyrin domain containing family of gene 12 (Nlrp12) are associated with periodic fever syndromes and atopic dermatitis in humans. Here, we have demonstrated a crucial role for NLRP12 in negatively regulating patho...

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Publicado en:Immunity
Autores principales: Lukens, John R., Gurung, Prajwal, Shaw, Patrick J., Barr, Margaret J., Zaki, Md. Hasan, Brown, Scott, Vogel, Peter, Chi, Hongbo, Kanneganti, Thirumala-Devi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412374/
https://ncbi.nlm.nih.gov/pubmed/25888258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.03.006
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