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Microfluidic high-throughput culturing of single cells for selection based on extracellular metabolite production or consumption
Phenotyping single cells based on the products they secrete or consume is a key bottleneck in many biotechnology applications, such as combinatorial metabolic engineering for the overproduction of secreted metabolites. Here we present a flexible high-throughput approach that uses microfluidics to co...
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| 出版年: | Nat Biotechnol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4412259/ https://ncbi.nlm.nih.gov/pubmed/24705516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2857 |
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