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Identification of giant Mimivirus protein functions using RNA interference

Genomic analysis of giant viruses, such as Mimivirus, has revealed that more than half of the putative genes have no known functions (ORFans). We knocked down Mimivirus genes using short interfering RNA as a proof of concept to determine the functions of giant virus ORFans. As fibers are easy to obs...

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Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Sobhy, Haitham, Scola, Bernard La, Pagnier, Isabelle, Raoult, Didier, Colson, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412084/
https://ncbi.nlm.nih.gov/pubmed/25972846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00345
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