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Proteomic analysis of media from lung cancer cells reveals role of 14-3-3 proteins in cachexia

Aims: At the time of diagnosis, 60% of lung cancer patients present with cachexia, a severe wasting syndrome that increases morbidity and mortality. Tumors secrete multiple factors that contribute to cachectic muscle wasting, and not all of these factors have been identified. We used Orbitrap electr...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: McLean, Julie B., Moylan, Jennifer S., Horrell, Erin M. W., Andrade, Francisco H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411971/
https://ncbi.nlm.nih.gov/pubmed/25972815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00136
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