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Essentiality and centrality in protein interaction networks revisited

BACKGROUND: Minimum dominating sets (MDSet) of protein interaction networks allow the control of underlying protein interaction networks through their topological placement. While essential proteins are enriched in MDSets, we hypothesize that the statistical properties of biological functions of ess...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Khuri, Sawsan, Wuchty, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411940/
https://ncbi.nlm.nih.gov/pubmed/25880655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0536-x
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