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Essentiality and centrality in protein interaction networks revisited

BACKGROUND: Minimum dominating sets (MDSet) of protein interaction networks allow the control of underlying protein interaction networks through their topological placement. While essential proteins are enriched in MDSets, we hypothesize that the statistical properties of biological functions of ess...

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Pubblicato in:BMC Bioinformatics
Autori principali: Khuri, Sawsan, Wuchty, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411940/
https://ncbi.nlm.nih.gov/pubmed/25880655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0536-x
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