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A TDG/CBP/RARα Ternary Complex Mediates the Retinoic Acid-dependent Expression of DNA Methylation-sensitive Genes

The thymine DNA glycosylase (TDG) is a multifunctional enzyme, which is essential for embryonic development. It mediates the base excision repair (BER) of G:T and G:U DNA mismatches arising from the deamination of 5-methyl cytosine (5-MeC) and cytosine, respectively. Recent studies have pointed at a...

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Detalhes bibliográficos
Publicado no:Genomics Proteomics Bioinformatics
Main Authors: Léger, Hélène, Smet-Nocca, Caroline, Attmane-Elakeb, Amel, Morley-Fletcher, Sara, Benecke, Arndt G., Eilebrecht, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411359/
https://ncbi.nlm.nih.gov/pubmed/24394593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gpb.2013.11.001
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https://ncbi.nlm.nih.gov/pmc/articles/PMC4411359/
https://ncbi.nlm.nih.gov/pubmed/24394593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gpb.2013.11.001