Osmosensing and scaffolding functions of the oligomeric four-transmembrane domain osmosensor Sho1

The yeast high osmolarity glycerol (HOG) pathway activates the Hog1 MAP kinase, which coordinates adaptation to high osmolarity conditions. Here we demonstrate that the four-transmembrane (TM) domain protein Sho1 is an osmosensor in the HKR1 sub-branch of the HOG pathway. Crosslinking studies indica...

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Publicado en:Nat Commun
Main Authors: Tatebayashi, Kazuo, Yamamoto, Katsuyoshi, Nagoya, Miho, Takayama, Tomomi, Nishimura, Akiko, Sakurai, Megumi, Momma, Takashi, Saito, Haruo
Formato: Artigo
Idioma:Inglês
Publicado: Nature Pub. Group 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411306/
https://ncbi.nlm.nih.gov/pubmed/25898136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7975
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