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Myosin light chain kinase regulates cell polarization independently of membrane tension or Rho kinase

Cells polarize to a single front and rear to achieve rapid actin-based motility, but the mechanisms preventing the formation of multiple fronts are unclear. We developed embryonic zebrafish keratocytes as a model system for investigating establishment of a single axis. We observed that, although ker...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Biol
Hauptverfasser: Lou, Sunny S., Diz-Muñoz, Alba, Weiner, Orion D., Fletcher, Daniel A., Theriot, Julie A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411279/
https://ncbi.nlm.nih.gov/pubmed/25918227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201409001
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