Evaluating the SERCA2 and VEGF mRNAs as Potential Molecular Biomarkers of the Onset and Progression in Huntington’s Disease

Abnormalities of intracellular Ca(2+) homeostasis and signalling as well as the down-regulation of neurotrophic factors in several areas of the central nervous system and in peripheral tissues are hallmarks of Huntington’s disease (HD). As there is no therapy for this hereditary, neurodegenerative f...

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Pubblicato in:PLoS One
Autori principali: Cesca, Federica, Bregant, Elisa, Peterlin, Borut, Zadel, Maja, Dubsky de Wittenau, Giorgia, Siciliano, Gabriele, Ceravolo, Roberto, Petrozzi, Lucia, Pauletto, Giada, Verriello, Lorenzo, Bergonzi, Paolo, Damante, Giuseppe, Barillari, Giovanni, Lucci, Bruno, Curcio, Francesco, Lonigro, Incoronata Renata
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411078/
https://ncbi.nlm.nih.gov/pubmed/25915065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125259
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