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Cytoplasmic Dynein Transports Cargos via Load-Sharing between the Heads

Cytoplasmic dynein is a motor protein that walks along microtubules (MTs) and performs mechanical work to power a variety of cellular processes. It remains unclear how a dynein dimer is able to transport cargos against load without coordinating the stepping cycles of its two heads. Here, by using a...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Belyy, Vladislav, Hendel, Nathan L., Chien, Alexander, Yildiz, Ahmet
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410804/
https://ncbi.nlm.nih.gov/pubmed/25424027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6544
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