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Dynamic caveolae exclude bulk membrane proteins and are required for sorting of excess glycosphingolipids

Caveolae have long been implicated in endocytosis. Recent data question this link, and in the absence of specific cargoes the potential cellular function of caveolar endocytosis remains unclear. Here we develop new tools, including doubly genome-edited cell lines, to assay the subcellular dynamics o...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Shvets, Elena, Bitsikas, Vassilis, Howard, Gillian, Hansen, Carsten Gram, Nichols, Benjamin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410672/
https://ncbi.nlm.nih.gov/pubmed/25897946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7867
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