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Interactions between horizontally acquired genes create a fitness cost in Pseudomonas aeruginosa

Horizontal gene transfer (HGT) plays a key role in bacterial evolution, especially with respect to antibiotic resistance. Fitness costs associated with mobile genetic elements (MGEs) are thought to constrain HGT, but our understanding of these costs remains fragmentary, making it difficult to predic...

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Pubblicato in:Nat Commun
Autori principali: San Millan, Alvaro, Toll-Riera, Macarena, Qi, Qin, MacLean, R. Craig
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410645/
https://ncbi.nlm.nih.gov/pubmed/25897488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7845
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