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Crystal structure of the Alcanivorax borkumensis YdaH transporter reveals an unusual topology

The potential of the folic acid biosynthesis pathway as a target for the development of antibiotics has been clinically validated. However, many pathogens have developed resistance to these antibiotics, prompting a reevaluation of potential drug targets within the pathway. The ydaH gene of Alcanivor...

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Vydáno v:Nat Commun
Hlavní autoři: Bolla, Jani Reddy, Su, Chih-Chia, Delmar, Jared A., Radhakrishnan, Abhijith, Kumar, Nitin, Chou, Tsung-Han, Long, Feng, Rajashankar, Kanagalaghatta R., Yu, Edward W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410182/
https://ncbi.nlm.nih.gov/pubmed/25892120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7874
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