Substrates Control Multimerization and Activation of the Multi-domain ATPase Motor of Type VII Secretion

Mycobacterium tuberculosis and Staphylococcus aureus secrete virulence factors via Type VII protein secretion (T7S), a system that intriguingly requires all of its secretion substrates for activity. To gain insights into T7S function, we used structural approaches to guide studies of the putative tr...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Rosenberg, Oren S., Dovala, Dustin, Li, Xueming, Connolly, Lynn, Bendebury, Anastasia, Finer-Moore, Janet, Holton, James, Cheng, Yifan, Stroud, Robert M., Cox, Jeffery S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409929/
https://ncbi.nlm.nih.gov/pubmed/25865481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.03.040
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