Phase I study of panobinostat plus everolimus in patients with relapsed or refractory lymphoma

PURPOSE: To evaluate the safety and efficacy of panobinostat plus everolimus in patients with relapsed Hodgkin and non-Hodgkin lymphoma. The concept was supported by the single agent clinical activity of histone deacetylase inhibitors and mTOR inhibitors, and on the in vitro mechanism-based synergis...

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Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Oki, Yasuhiro, Buglio, Daniela, Fanale, Michelle, Fayad, Luis, Copeland, Amanda, Romaguera, Jorge, Kwak, Larry W., Pro, Barbara, de Castro Faria, Silvana, Neelapu, Sattva, Fowler, Nathan, Hagemeister, Fredrick, Zhang, Jiexin, Zhou, Shouhao, Feng, Lei, Younes, Anas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409814/
https://ncbi.nlm.nih.gov/pubmed/24097867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1906
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