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Altered PPP2R2A and Cyclin D1 expression defines a subgroup of aggressive luminal-like breast cancer

BACKGROUND: PPP2R2A deletions were recently linked to a subgroup of luminal breast carcinoma (BC) that exhibits poor survival. This subgroup also exhibited amplification of a chromosome region containing the Cyclin D1 coding gene, CCND1. Therefore, we aimed to investigate whether a combination of PP...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Beca, Francisco, Pereira, Miguel, Cameselle-Teijeiro, Jorge F, Martins, Diana, Schmitt, Fernando
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409761/
https://ncbi.nlm.nih.gov/pubmed/25879784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1266-1
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