Human Gene-Centered Transcription Factor Networks for Enhancers and Disease Variants

Gene regulatory networks (GRNs) comprising interactions between transcription factors (TFs) and regulatory loci control development and physiology. Numerous disease-associated mutations have been identified, the vast majority residing in non-coding regions of the genome. As current GRN mapping metho...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Bass, Juan I. Fuxman, Sahni, Nidhi, Shrestha, Shaleen, Garcia-Gonzalez, Aurian, Mori, Akihiro, Bhat, Numana, Yi, Song, Hill, David E., Vidal, Marc, Walhout, Albertha J.M.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409666/
https://ncbi.nlm.nih.gov/pubmed/25910213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.03.003
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