Fingolimod and CSF neurofilament light chain levels in relapsing-remitting multiple sclerosis

OBJECTIVE: We assessed CSF levels of the light chain subunit of neurofilaments (NfL) at baseline and after fingolimod therapy or placebo in patients with relapsing-remitting multiple sclerosis (RRMS). Changes in NfL levels were also correlated with relapse and MRI outcomes. METHODS: CSF samples were...

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Veröffentlicht in:Neurology
Hauptverfasser: Kuhle, Jens, Disanto, Giulio, Lorscheider, Johannes, Stites, Tracy, Chen, Yu, Dahlke, Frank, Francis, Gordon, Shrinivasan, Anupama, Radue, Ernst-Wilhelm, Giovannoni, Gavin, Kappos, Ludwig
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409586/
https://ncbi.nlm.nih.gov/pubmed/25809304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001491
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