GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma

BACKGROUND: Intraductal papillary mucinous neoplasms (IPMN) are being increasingly recognized as important precursors to pancreatic adenocarcinoma. Elucidation of the genetic changes underlying IPMN carcinogenesis may improve the diagnosis and management of IPMN. We sought to determine whether diffe...

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Publicado en:J Am Coll Surg
Autores principales: Tan, Marcus C, Basturk, Olca, Brannon, A Rose, Bhanot, Umesh, Scott, Sasinya N, Bouvier, Nancy, LaFemina, Jennifer, Jarnagin, William R, Berger, Michael F, Klimstra, David, Allen, Peter J
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409519/
https://ncbi.nlm.nih.gov/pubmed/25840541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2014.11.029
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