GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma

BACKGROUND: Intraductal papillary mucinous neoplasms (IPMN) are being increasingly recognized as important precursors to pancreatic adenocarcinoma. Elucidation of the genetic changes underlying IPMN carcinogenesis may improve the diagnosis and management of IPMN. We sought to determine whether diffe...

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Detalhes bibliográficos
Publicado no:J Am Coll Surg
Main Authors: Tan, Marcus C, Basturk, Olca, Brannon, A Rose, Bhanot, Umesh, Scott, Sasinya N, Bouvier, Nancy, LaFemina, Jennifer, Jarnagin, William R, Berger, Michael F, Klimstra, David, Allen, Peter J
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409519/
https://ncbi.nlm.nih.gov/pubmed/25840541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2014.11.029
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