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d-Cycloserine combined with cue exposure therapy fails to attenuate subjective and physiological craving in cocaine dependence

BACKGROUND: Based on preclinical studies showing that the partial N-methyl-d-aspartate (NMDA) agonist d-cycloserine (DCS) facilitates extinction of cocaine self-administration and cocaine-induced conditioned place preference, we evaluated whether 50 mg of DCS would reduce craving to cocaine cues whe...

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Detalhes bibliográficos
Publicado no:Am J Addict
Main Authors: Santa Ana, Elizabeth J., Prisciandaro, James J., Saladin, Michael E., McRae-Clark, Aimee L., Shaftman, Stephanie R., Nietert, Paul J., Brady, Kathleen T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409457/
https://ncbi.nlm.nih.gov/pubmed/25808169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajad.12191
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