Genetic Analysis Using an Isogenic Mating Pair of Aspergillus fumigatus Identifies Azole Resistance Genes and Lack of MAT Locus’s Role in Virulence

Invasive aspergillosis (IA) due to Aspergillus fumigatus is a major cause of mortality in immunocompromised patients. The discovery of highly fertile strains of A. fumigatus opened the possibility to merge classical and contemporary genetics to address key questions about this pathogen. The merger i...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Losada, Liliana, Sugui, Janyce A., Eckhaus, Michael A., Chang, Yun C., Mounaud, Stephanie, Figat, Abigail, Joardar, Vinita, Pakala, Suman B., Pakala, Suchitra, Venepally, Pratap, Fedorova, Natalie, Nierman, William C., Kwon-Chung, Kyung J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409388/
https://ncbi.nlm.nih.gov/pubmed/25909486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004834
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