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Cytotoxic Effects during Knock Out of Multiple Porcine Endogenous Retrovirus (PERV) Sequences in the Pig Genome by Zinc Finger Nucleases (ZFN)

Xenotransplantation has been proposed as a solution to the shortage of suitable human donors for transplantation and pigs are currently favoured as donor animals. However, xenotransplantation may be associated with the transmission of zoonotic microorganisms. Whereas most porcine microorganisms repr...

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Pubblicato in:PLoS One
Autori principali: Semaan, Marwan, Ivanusic, Daniel, Denner, Joachim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409370/
https://ncbi.nlm.nih.gov/pubmed/25909512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122059
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