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Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262

The crystal structure of a fully glycosylated HIV-1 gp120 core in complex with CD4 receptor and Fab 17b at 4.5 Å resolution reveals 9 of the 15 N-linked glycans of core gp120 to be partially ordered. The glycan at position Asn262 had the most extensive and well-ordered electron density, and a GlcNAc...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Kong, Leopold, Wilson, Ian A., Kwong, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409329/
https://ncbi.nlm.nih.gov/pubmed/25546301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24747
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