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Identification of glutathione adducts of α-chlorofatty aldehydes produced in activated neutrophils

α-Chlorofatty aldehydes (α-ClFALDs) are produced by hypochlorous acid targeting plasmalogens during neutrophil activation. This study investigated the reaction of the α-chlorinated carbon of α-ClFALD with the nucleophile, GSH. Utilizing ESI/MS/MS, the reaction product of GSH and the 16-carbon α-ClFA...

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Pubblicato in:J Lipid Res
Autori principali: Duerr, Mark A., Aurora, Rajeev, Ford, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409278/
https://ncbi.nlm.nih.gov/pubmed/25814023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M058636
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