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Trans-sulfuration Pathway Seleno-amino Acids Are Mediators of Selenomethionine Toxicity in Saccharomyces cerevisiae*

Toxicity of selenomethionine, an organic derivative of selenium widely used as supplement in human diets, was studied in the model organism Saccharomyces cerevisiae. Several DNA repair-deficient strains hypersensitive to selenide displayed wild-type growth rate properties in the presence of selenome...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Lazard, Myriam, Dauplais, Marc, Blanquet, Sylvain, Plateau, Pierre
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409240/
https://ncbi.nlm.nih.gov/pubmed/25745108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.640375
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