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Ae4 (Slc4a9) Anion Exchanger Drives Cl(−) Uptake-dependent Fluid Secretion by Mouse Submandibular Gland Acinar Cells

Transcellular Cl(−) movement across acinar cells is the rate-limiting step for salivary gland fluid secretion. Basolateral Nkcc1 Na(+)-K(+)-2Cl(−) cotransporters play a critical role in fluid secretion by promoting the intracellular accumulation of Cl(−) above its equilibrium potential. However, sal...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Peña-Münzenmayer, Gaspar, Catalán, Marcelo A., Kondo, Yusuke, Jaramillo, Yasna, Liu, Frances, Shull, Gary E., Melvin, James E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409235/
https://ncbi.nlm.nih.gov/pubmed/25745107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.612895
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