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From big data to mechanism

The gene variant APOE4 is the most common genetic risk factor associated with late-onset Alzheimer’s disease. A comprehensive, multilayer study reveals the molecular and cellular signatures of APOE4 in humans.

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Bibliographic Details
Published in:Nature
Main Authors: Swarup, Vivek, Geschwind, Daniel H.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409124/
https://ncbi.nlm.nih.gov/pubmed/23883924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12457
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