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Coupled local translation and degradation regulate growth cone collapse
Local translation mediates axonal responses to Semaphorin3A (Sema3A) and other guidance cues. However, only a subset of the axonal proteome is locally synthesized, while most proteins are trafficked from the soma. The reason why only specific proteins are locally synthesized is unknown. Here we show...
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| Published in: | Nat Commun |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408908/ https://ncbi.nlm.nih.gov/pubmed/25901863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7888 |
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