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Radiation inactivation of human gamma-interferon: cellular activation requires two dimers.

gamma-Interferon (IFN-gamma) is a 17-kDa broad-spectrum cytokine which exerts its effects on a variety of target cells through its interaction with the IFN-gamma receptor. Although physicochemical studies of Escherichia coli-derived IFN-gamma, as well as its crystal structure, demonstrate that it is...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Langer, J A, Rashidbaigi, A, Garotta, G, Kempner, E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44088/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8016072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.5818
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