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Metazoan Maelstrom is an RNA-binding protein that has evolved from an ancient nuclease active in protists
Piwi-interacting RNAs (piRNAs) guide Piwi argonautes to their transposon targets for silencing. The highly conserved protein Maelstrom is linked to both piRNA biogenesis and effector roles in this pathway. One defining feature of Maelstrom is the predicted MAEL domain of unknown molecular function....
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| Udgivet i: | RNA |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408791/ https://ncbi.nlm.nih.gov/pubmed/25778731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.049437.114 |
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