Metazoan Maelstrom is an RNA-binding protein that has evolved from an ancient nuclease active in protists

Piwi-interacting RNAs (piRNAs) guide Piwi argonautes to their transposon targets for silencing. The highly conserved protein Maelstrom is linked to both piRNA biogenesis and effector roles in this pathway. One defining feature of Maelstrom is the predicted MAEL domain of unknown molecular function....

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Publicat a:RNA
Autors principals: Chen, Kuan-Ming, Campbell, Edgar, Pandey, Radha Raman, Yang, Zhaolin, McCarthy, Andrew A., Pillai, Ramesh S.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2015
Matèries:
Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408791/
https://ncbi.nlm.nih.gov/pubmed/25778731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.049437.114
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