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Metazoan Maelstrom is an RNA-binding protein that has evolved from an ancient nuclease active in protists

Piwi-interacting RNAs (piRNAs) guide Piwi argonautes to their transposon targets for silencing. The highly conserved protein Maelstrom is linked to both piRNA biogenesis and effector roles in this pathway. One defining feature of Maelstrom is the predicted MAEL domain of unknown molecular function....

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Bibliografiske detaljer
Udgivet i:RNA
Main Authors: Chen, Kuan-Ming, Campbell, Edgar, Pandey, Radha Raman, Yang, Zhaolin, McCarthy, Andrew A., Pillai, Ramesh S.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408791/
https://ncbi.nlm.nih.gov/pubmed/25778731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.049437.114
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