Hypoxic Regulation of Functional Extracellular Matrix Elaboration by Nucleus Pulposus Cells in Long-Term Agarose Culture

Degeneration of the intervertebral discs is strongly implicated as a cause of low back pain. Since current treatments for discogenic low back pain show poor long-term efficacy, a number of new, biological strategies are being pursued. For such therapies to succeed, it is critical that they be valida...

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Publicat a:J Orthop Res
Autors principals: Gorth, Deborah J, Lothstein, Katherine E, Chiaro, Joseph A, Farrell, Megan J, Dodge, George R, Elliott, Dawn M, Malhotra, Neil R, Mauck, Robert L, Smith, Lachlan J
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408762/
https://ncbi.nlm.nih.gov/pubmed/25640328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22821
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