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Differential Effects of Oral Exposure to Naturally-Occurring and Synthetic Deoxynivalenol Congeners on Proinflammatory Cytokine and Chemokine mRNA Expression in the Mouse
The foodborne mycotoxin deoxynivalenol (DON) induces a ribotoxic stress response in mononuclear phagocytes that mediate aberrant multi-organ upregulation of TNF-α, interleukins and chemokines in experimental animals. While other DON congeners also exist as food contaminants or pharmacologically-acti...
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| Publicado no: | Toxicol Appl Pharmacol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408533/ https://ncbi.nlm.nih.gov/pubmed/24793808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.04.016 |
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