Reduced CD5(+)CD24(hi)CD38(hi) and interleukin-10(+) regulatory B cells in active anti-neutrophil cytoplasmic autoantibody-associated vasculitis permit increased circulating autoantibodies

Pathogenesis of anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis is B cell-dependent, although how particular B cell subsets modulate immunopathogenesis remains unknown. Although their phenotype remains controversial, regulatory B cells (B(regs)), play a role in immunological to...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Aybar, L T, McGregor, J G, Hogan, S L, Hu, Y, Mendoza, C E, Brant, E J, Poulton, C J, Henderson, C D, Falk, R J, Bunch, D O
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Translational
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408152/
https://ncbi.nlm.nih.gov/pubmed/25376552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12483
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