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A Small Antigenic Determinant of the Chikungunya Virus E2 Protein Is Sufficient to Induce Neutralizing Antibodies which Are Partially Protective in Mice

BACKGROUND: The mosquito-borne Chikungunya virus (CHIKV) causes high fever and severe joint pain in humans. It is expected to spread in the future to Europe and has recently reached the USA due to globalization, climate change and vector switch. Despite this, little is known about the virus life cyc...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Weber, Christopher, Büchner, Sarah M., Schnierle, Barbara S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407984/
https://ncbi.nlm.nih.gov/pubmed/25905779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003684
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