The Stress-responsive Gene ATF3 Regulates the Histone Acetyltransferase Tip60

Tat-interactive protein 60 (Tip60) is a MYST histone acetyltransferase that catalyzes acetylation of the major DNA damage kinase ATM, thereby triggering cellular signaling required for the maintenance of genomic stability upon genotoxic insults. The Tip60 activity is modulated by posttranslational m...

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Udgivet i:Nat Commun
Main Authors: Cui, Hongmei, Guo, Mingxiong, Xu, Dong, Ding, Zhi-Chun, Zhou, Gang, Ding, Han-Fei, Zhang, Junran, Tang, Yi, Yan, Chunhong
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407828/
https://ncbi.nlm.nih.gov/pubmed/25865756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7752
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