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Mechanistic Insights into Elastin Degradation by Pseudolysin, the Major Virulence Factor of the Opportunistic Pathogen Pseudomonas aeruginosa

Pseudolysin is the most abundant protease secreted by Pseudomonas aeruginosa and is the major extracellular virulence factor of this opportunistic human pathogen. Pseudolysin destroys human tissues by solubilizing elastin. However, the mechanisms by which pseudolysin binds to and degrades elastin re...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yang, Jie, Zhao, Hui-Lin, Ran, Li-Yuan, Li, Chun-Yang, Zhang, Xi-Ying, Su, Hai-Nan, Shi, Mei, Zhou, Bai-Cheng, Chen, Xiu-Lan, Zhang, Yu-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407726/
https://ncbi.nlm.nih.gov/pubmed/25905792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09936
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