Granulysin-Derived Peptides Demonstrate Antimicrobial and Anti-Inflammatory Effects Against Propionibacterium acnes

Propionibacterium acnes is a key therapeutic target in acne, yet this bacterium has become resistant to standard antibiotic agents. We investigated whether the human antimicrobial protein granulysin is a potential candidate for the treatment of acne. Granulysin and synthetic granulysin-derived pepti...

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Détails bibliographiques
Publié dans:J Invest Dermatol
Auteurs principaux: McInturff, Jamie E., Wang, Shyh-Jeun, Machleidt, Thomas, Lin, T. Richard, Oren, Ami, Hertz, Cheryl J., Krutzik, Stephan R., Hart, Scott, Zeh, Karin, Anderson, Daniel H., Gallo, Richard L., Modlin, Robert L., Kim, Jenny
Format: Artigo
Langue:Inglês
Publié: 2005
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407689/
https://ncbi.nlm.nih.gov/pubmed/16098035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0022-202X.2005.23805.x
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