PDGF beta targeting in cervical cancer cells suggest a fine-tuning of compensatory signalling pathways to sustain tumourigenic stimulation

The platelet-derived growth factor (PDGF) signalling pathway has been reported to play an important role in human cancers by modulating autocrine and paracrine processes such as tumour growth, metastasis and angiogenesis. Several clinical trials document the benefits of targeting this pathway; howev...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Tudoran, Oana Mihaela, Soritau, Olga, Balacescu, Loredana, Pop, Laura, Meurice, Guillaume, Visan, Simona, Lindberg, Staffan, Eniu, Alexandru, Langel, Ulo, Balacescu, Ovidiu, Berindan-Neagoe, Ioana
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407607/
https://ncbi.nlm.nih.gov/pubmed/25311137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12449
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