Sitagliptin attenuates sympathetic innervation via modulating reactive oxygen species and interstitial adenosine in infarcted rat hearts

We investigated whether sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, attenuates arrhythmias through inhibiting nerve growth factor (NGF) expression in post-infarcted normoglycemic rats, focusing on adenosine and reactive oxygen species production. DPP-4 bound adenosine deaminase has been...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Lee, Tsung-Ming, Chen, Wei-Ting, Yang, Chen-Chia, Lin, Shinn-Zong, Chang, Nen-Chung
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407589/
https://ncbi.nlm.nih.gov/pubmed/25388908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12465
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