Valproic acid attenuates intercellular adhesion molecule-1 and E-selectin through a chemokine ligand 5 dependent mechanism and subarachnoid hemorrhage induced vasospasm in a rat model

BACKGROUND: Up-regulation of regulated upon activation, normal T-cell expressed and secreted (RANTES/CCL5) and adhesion molecules is observed in the serum of animals following experimental subarachnoid hemorrhage (SAH). The present study was to examine the effect of valproic acid (VPA) on RANTES and...

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Detalles Bibliográficos
Publicado en:J Inflamm (Lond)
Main Authors: Chang, Chih-Zen, Wu, Shu-Chuan, Lin, Chih-Lung, Kwan, Aij-Lie
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407545/
https://ncbi.nlm.nih.gov/pubmed/25908928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-015-0074-3
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