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Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro
BACKGROUND: Neuro-inflammation has long been implicated as a contributor to the progression of Alzheimer’s disease in both humans and animal models. Type-1 interferons (IFNs) are pleiotropic cytokines critical in mediating the innate immune pro-inflammatory response. The production of type-1 IFNs fo...
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| Published in: | J Neuroinflammation |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407532/ https://ncbi.nlm.nih.gov/pubmed/25879763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0263-2 |
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