Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro

BACKGROUND: Neuro-inflammation has long been implicated as a contributor to the progression of Alzheimer’s disease in both humans and animal models. Type-1 interferons (IFNs) are pleiotropic cytokines critical in mediating the innate immune pro-inflammatory response. The production of type-1 IFNs fo...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Minter, Myles Robert, Main, Bevan Scott, Brody, Kate Maree, Zhang, Moses, Taylor, Juliet Marie, Crack, Peter John
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407532/
https://ncbi.nlm.nih.gov/pubmed/25879763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0263-2
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