Chitinase 3–like-1 Regulates Both Visceral Fat Accumulation and Asthma-like Th2 Inflammation

Rationale: Obesity, especially truncal obesity, is a risk factor for asthma incidence, prevalence, and severity. Chitinase 3–like-1 (Chi3l1) is an evolutionarily conserved moiety that plays a critical role in antipathogen and Th2 responses. However, the mechanisms that underlie the association betwe...

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Vydáno v:Am J Respir Crit Care Med
Hlavní autoři: Ahangari, Farida, Sood, Akshay, Ma, Bing, Takyar, Seyedtaghi, Schuyler, Mark, Qualls, Clifford, Dela Cruz, Charles S., Chupp, Geoffrey L., Lee, Chun G., Elias, Jack A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407482/
https://ncbi.nlm.nih.gov/pubmed/25629580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201405-0796OC
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