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Molecular Cloning of Drosophila HCF Reveals Proteolytic Processing and Self-Association of the Encoded Protein

HCF-1 functions as a coactivator for herpes simplex virus VP16 and a number of mammalian transcription factors. Mature HCF-1 is composed of two subunits generated by proteolytic cleavage of a larger precursor at six centrally-located HCF(PRO) repeats. The resulting N-and C-terminal subunits remain t...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Mahajan, Shahana S., Johnson, Kristina M., Wilson, Angus C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407374/
https://ncbi.nlm.nih.gov/pubmed/12494450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.10193
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