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Evolutionary Engineering Improves Tolerance for Replacement Jet Fuels in Saccharomyces cerevisiae

Monoterpenes are liquid hydrocarbons with applications ranging from flavor and fragrance to replacement jet fuel. Their toxicity, however, presents a major challenge for microbial synthesis. Here we evolved limonene-tolerant Saccharomyces cerevisiae strains and sequenced six strains across the 200-g...

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Bibliografiske detaljer
Udgivet i:Appl Environ Microbiol
Main Authors: Brennan, Timothy C. R., Williams, Thomas C., Schulz, Benjamin L., Palfreyman, Robin W., Krömer, Jens O., Nielsen, Lars K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407233/
https://ncbi.nlm.nih.gov/pubmed/25746998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.04144-14
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