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Methyl-CpG binding protein 2 regulates microglia and macrophage gene expression in response to inflammatory stimuli

Mutations in MECP2, encoding the epigenetic regulator methyl-CpG-binding protein 2, are the predominant cause of Rett syndrome, a disease characterized by both neurological symptoms and systemic abnormalities. Microglial dysfunction is thought to contribute to disease pathogenesis, and here we found...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Cronk, James C., Derecki, Noël C., Ji, Emily, Xu, Yang, Lampano, Aaron E., Smirnov, Igor, Baker, Wendy, Norris, Geoffrey T., Marin, Ioana, Coddington, Nathan, Wolf, Yochai, Turner, Stephen D., Aderem, Alan, Klibanov, Alexander L., Harris, Tajie H., Jung, Steffen, Litvak, Vladimir, Kipnis, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407145/
https://ncbi.nlm.nih.gov/pubmed/25902482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.03.013
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