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The mechanisms of action of vaccines containing aluminum adjuvants: an in vitro vs in vivo paradigm

Adjuvants such as the aluminum compounds (alum) have been dominantly used in many vaccines due to their immunopotentiation and safety records since 1920s. However, how these mineral agents influence the immune response to vaccination remains elusive. Many hypotheses exist as to the mode of action of...

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Publicado no:Springerplus
Autor principal: Ghimire, Tirth Raj
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406982/
https://ncbi.nlm.nih.gov/pubmed/25932368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-015-0972-0
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